Sarah Hussain

Transplant Oncology and Inf. Diseases (TOID), Johns Hopkins Medicine.

• Participate as a collaborative member of the senior research team, serving as the content specialist on data management aspects for clinical trials including start-up, maintenance, and close-out activities.
• Designing, building and implementing databases for research studies conducted under division of Transplant Oncology and Infectious Diseases Department, JHU. Creating Electronic Data Capture systems in REDCap.
• Develop study specific electronic or paper Case Report Forms (CRFs), ensuring consistency with study protocol and /or clinical requirements.
• Management of data collection, verification, cleaning, and quality for accurate reporting of results of multiple research projects.
• Creating and maintaining data management documents such as Data Management Plans, Data Validation Plans, Data Entry Guidelines and Data Transfer Agreements.
• Conducting data quality checks to ensure data are in accordance with Good Clinical Practices (GCP) and study protocols.
• Designing and generating data queries and reports to expedite site -specific data queries resolution ensuring accurate data collection.
• Prepare reports for data presentations.
• Responsible for overseeing database lock and transfer process.
• Train peers, contribute to peer selection, performance evaluation, peer orientation and project communications for the Data Management division of Transplant Oncology and Infectious Diseases Department, JHU.

Division of Hematology, Johns Hopkins Medicine.

• Orchestrated data management for phase 2 multi-centered clinical trial of ACH-0144471 drug in patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) by collaborating with patient care teams, clinical study sponsors and third party medical monitors. Successfully managed the Johns Hopkins site by conducting data mining from electronic medical records, managing electronic data capture in RAVE electronic data capture (EDC) systems, collaborating with a team of medical monitors from InSeption Group (https://inseptiongroup.com) to maintain patient eligibility, follow up, safety, adherence and outcomes. Managed the trial workflow redesign during COVID pandemic to maintain patient safety and study compliance.
• Primary data manager of The International PNH Registry (https://pnhregistry.com) which was established in 2012 to gather comprehensive data on the natural history of Paroxysmal Nocturnal Hemoglobinurea and to evaluate the clinical symptoms and outcomes of the disease in order to better understand progression and variability of the disease on a global scale. Streamlined processes to gather and report non-interventional observational data in reliable form. Collaborated with medical monitors to troubleshoot all data reporting queries.
• Primary database manager for Globin Regional Data and Discovery (GRNDaD) registry (https://grndad.org/). Supervised and supported 15 sites across United States in effectively capturing and reporting prospective data on more than 2000 sickle cell disease patients. After inheriting the project in 2019, successfully steered all operational roadblocks by building a robust data capture system within REDCap. Designed study specific paper Case Report Forms (CRFs), ensuring consistency with study protocol. Established intuitive data capture instruments in REDCap to capture the not only the disease specific data but also COVID-19 information among the sickle cell anemia patients in the country.
• Spearheaded the process of designing, coding, building and implementing 11 electronic data capture systems in REDCap for single-site research studies on Thrombotic thrombocytopenic purpura, Sickle cell disease, Antiphospholipid disease, Systemic lupus erythematosus and Idiopathic thrombocytopenic purpura conducted under division of Hematology, JHU. Collaborated with principal investigators to create all data management and validation plans.
• Primary analyst for the Johns Hopkins Sickle Cell-Infusion Clinic quality improvement initiative. Used operational data to report loopholes in patient care and staff performance. Generated evidence-based data-driven visualization dashboards and charts on recurring monthly basis. This process involved data mining and cleaning exercises, analyses and presenting reports to stakeholders of the clinic.
• Successfully worked as primary analyst for 8 manuscripts published in peer reviewed journals.

• Developed Tableau-based data visualization systems to study risk factors for non-communicable diseases in Bangladesh, Tanzania, Colombia, and Uganda.
• Collaborated with a Bangladeshi software development team to create JavaScript live data connectors for visualizing data in real- time.
• Analyzed 5-arm randomized studies in Colombia and Uganda for Mobile Phone Survey consent, alternative disclosure, and methods of authorization.

• Investigated the causes for why physicians ignored Epic-prompted best practice advisory alerts (BPAs) for Naloxone prescriptions 60% of the time for 2400 BPAs.
• Conducted three-part intervention to improve physician-BPA adherence: physician BPA education, naloxone education, and developed performance audits of Physician usage of Epic in prescribing naloxone.
• Created a 19% improvement in the naloxone prescribing rates at Johns Hopkins University.

• Conducted operational analysis detailing the workflow from initialization of Epic-prompted smoking cessation BPAs to final referral to Maryland Quit-line.
• Developed workflow diagrams that illustrate the relevant operational processes in the Epic referral process to visualize Epic incorporation into multiple health organizations.

• For Biomedical and Public Health Informatics, a masters-level course at Johns Hopkins University.
• Responsible for being the subject matter expert for 45 students, answering questions, grading coursework, and conducting live talks with individuals involved in public health informatics and bioinformatics.
• Subject matter includes: Informatics deployment, data integration, outcome analysis, information systems, and more.

• Observed patients' conditions by measuring output and vital signs, reporting significant changes to staff through chain of command.
• Analyzed and interpreted patients' histories, symptoms, physical findings and diagnostic information to develop appropriate diagnosis.

• Analyzed and interpreted patients' histories, symptoms, physical findings and diagnostic information to develop appropriate diagnosis.
• Cultivated rapport with patients and caregivers, utilizing proactive communication with parents and children.

• Involved in primary medical care of all outpatient visits.
• Recording and analyzing patient histories and presenting complaints at the time of visit.
• Prescribing appropriate medical treatment and/or referrals.

• Analyzed patients' medical histories, medication allergies, physical conditions and examination results to determine best procedure.
• Educated patients on recovery methods and times.
• Conducted various common surgical procedures such as appendectomies, hemorrhoidectomies, inguinal hernia repairs and tonsillectomies to restore health in patients.
• Performed minor, outpatient surgical procedures.