Summary
Overview
Work History
Education
Skills
Accomplishments
Languages
Timeline
Thanh Tran

Thanh Tran

San Diego,CA

Summary

Dedicated and highly self-motivated professional with extensive technical expertise in the synthesis and purification of oligonucleotides and fluorescent dye nucleotides. Proficient in cGMP and FDA compliance, with a strong background in process development, production planning, and problem-solving within manufacturing environments. Exceptional collaboration skills enable effective contributions to both self-managed projects and team-oriented settings. Solid working knowledge of C++ programming, Microsoft Office, Unicorn OligoPilot, Unicorn Chromatography systems, Agilent ChemStation, MassHunter, BioConfirm software, and ERP systems such as NetSuite and SAP. Excellent lab instrumentation skills include calibrating, troubleshooting, and safely operating laboratory equipment.

Overview

26
26
years of professional experience

Work History

Senior Production Chemist

SIRO Diagnostics Inc.
09.2024 - Current
  • Participated in setting up Oligonucleotide lab, performing reagents, supply and consumable inventory.
  • Installing various lab instruments and performing internal IQ/OQ to ensure it can be used for R&D and production purposes.
  • Developing Oligo synthesis methods, purification methods, analytical methods and performing various chromatography characterization of manufactured oligonucleotide including Analytical Hplc, LCMS and UV vis.

Senior Production Scientist

Cue Health Inc.
12.2021 - 05.2024
  • Leading projects in improving Oligonucleotide yield and quality by developing and optimizing manufacture processes.
  • Developing ÄKTA OligoPilot 100 synthesizer methods, ÄKTA Avant, ÄKTA Pilot purification methods and performing various chromatography characterization for the novel conjugated Oligonucleotide-HRP products.
  • Providing technical support to production team, troubleshooting issues emerging from daily manufacturing tasks.

Senior Manufacturing Associate/Manufacturing Specialist 5

Illumina Inc.
06.2012 - 12.2021
  • Synthesized and purified various dye conjugated modified nucleotide products using Organic synthesis Chemistry following cGMP guideline.
  • Performing lab instrumentation onboarding, creating daily and weekly synthesizer maintenance processes, troubleshooting and basic repairing for Oligo synthesizers, Hplc purification and analytical equipment.
  • Scheduled production, prepared and allocated raw materials for the manufacturing group.
  • Created and edited work instructions, batch records for different processes and products.
  • Participated in several new product transfer projects, and various process development projects.
  • Collaborated with Manufacturing Technical Operation group in different manufacturing process development projects.

Senior Production Chemist

Illumina Inc.
02.2012 - 06.2012
  • Prepared various library primer mix, reagents, buffers for SBS sequencing application.
  • Participated in setting up new production lab, assisted in equipment installation, ordered raw material and labware consumable.
  • Participated in creating and editing work instructions, batch records for a new production line.

Oligonucleotide Chemist - Synthesis Task Manager

Tri-Link Biotechnology Inc.
02.2003 - 12.2011
  • Participated in process development for synthesis and chromatographic purification of various types of Oligonucleotides under QSR guidelines.
  • Constructed and revised standard operating procedures for Oligonucleotide production.
  • Trained and oversaw technicians for various synthesis tasks.
  • Operated and maintained ÄKTA OligoPilot synthesizer, 3900 ABI Synthesizer, ÄKTA Explorer HPLC system, dial-filtration system, PAGE system, spectrophotometers and other lab instruments.

DNA Synthesis Team Leader

ProLigo LLC/Genset Oligos Corp
11.1999 - 02.2003
  • Synthesized and performed quality control wide variety of custom Oligonucleotides including Light Cycler, modified and labeled nuclease probes.
  • Assisted the manager in organizing and supervising the synthesis team.
  • Involved in the construction and revision of standard operating procedures.
  • Performed inventory tracking of materials and reagents.

Education

Bachelor of Science - Biochemistry/Chemistry

University of California San Diego

Skills

  • Process optimization
  • Operational planning
  • Effective problem resolution
  • QSR industry experience
  • Biomolecule separation methods
  • Skilled in Microsoft Office tools
  • Experience with Unicorn OligoPilot
  • Proficient in Unicorn chromatography system control
  • Agilent ChemStation operation
  • Experienced with MassHunter BioConfirm analysis
  • ERP software proficiency
  • Safe operation of lab instrumentation

Accomplishments

  • Supervised team of 5 staff members.
  • Used Microsoft Excel to develop inventory tracking spreadsheets.
  • Documented and resolved [Issue] which led to [Results].
  • Collaborated with team of [Number] in the development of [Project name].
  • Achieved [Result] by completing [Task] with accuracy and efficiency.

Languages

English
Professional Working

Timeline

Senior Production Chemist - SIRO Diagnostics Inc.
09.2024 - Current
Senior Production Scientist - Cue Health Inc.
12.2021 - 05.2024
Senior Manufacturing Associate/Manufacturing Specialist 5 - Illumina Inc.
06.2012 - 12.2021
Senior Production Chemist - Illumina Inc.
02.2012 - 06.2012
Oligonucleotide Chemist - Synthesis Task Manager - Tri-Link Biotechnology Inc.
02.2003 - 12.2011
DNA Synthesis Team Leader - ProLigo LLC/Genset Oligos Corp
11.1999 - 02.2003
University of California San Diego - Bachelor of Science, Biochemistry/Chemistry

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Thanh Tran