Anuradha A. Shastri
Berwyn,USA
Summary
- Self-motivated life scientist with extensive experience leading and managing preclinical projects in the areas of oncology, nutrition, and metabolic disorders research, leading to translational research and 8 publications.
- Strong leadership skills and managerial experience training and mentoring research professionals, leading to collaborative work on research for NIH grants.
- Extensive experience in scientific and grant writing demonstrates a strong ability to effectively communicate complex research concepts.
Overview
13
13
years of professional experience
1
1
Certification
Work History
Post-Doctoral Fellow
Thomas Jefferson University
Philadelphia, PA
05.2019 - 10.2023
- Designed and led in vitro and in vivo research to investigate if metabolic interventions enhanced radiation therapy outcomes in breast and prostate cancers.
- Investigated strategies to reduce normal tissue toxicity associated with radiation treatment.
- Investigated the effect of metabolic interventions on anti-tumor immune response.
- Elucidated the mechanisms underlying breast cancer metastasis and explored novel therapeutic approaches.
- Conducted research to improve treatment outcomes for African American women with breast cancer.
- Studied the impact of microRNAs on drug resistance in breast and prostate cancer.
- Analyzed patient tumor and other tissue samples to determine the effect of treatment on inflammatory biomarkers and signaling pathways using cDNA profiling and studying gut microbiome.
- Communicated research findings, presentations, and publications.
- Trained and mentored junior researchers.
Postdoctoral Research Associate/Laboratory Manager
Texas Tech University
Lubbock, TX
02.2016 - 08.2017
- Designed and led an in vitro study to determine the mechanism used by the novel anti-diabetic drug candidate Ad36E4orfl to enhance cellular glucose uptake in the absence of insulin.
- Designed and led an in vivo study to investigate hyperglycemia in mice using insulin pathway inhibitors S961, PPP, and Wortmannin.
- Standardized and validated protocols to increase efficiency of the laboratory.
- Mentored and trained other lab researchers, and supervised their projects.
- Helped set up the new BSL2 in the department.
Lead Teaching Assistant
Texas Tech University
Lubbock, TX
01.2011 - 12.2015
- Taught and mentored over 300 students throughout four years, teaching them the foundational principles of nutritional science.
- Evaluated student progress through written reports to provide personalized feedback and guidance.
- Cultivated a collaborative learning environment by managing and training new teaching assistants.
- Ensured consistent standards and positive experiences for students.
- Designed comprehensive syllabi and teaching schedules to foster student engagement and facilitate a successful learning path.
Ph.D. Candidate
Texas Tech University
Lubbock, USA
01.2011 - 12.2015
- Conceptualized, designed, and worked on an in vitro study to determine if alcohols follow redox cycling similar to sulfur and selenium compounds to generate superoxide.
- Tested the discovery of oxides' redox cycling in cancer cells using ROS detection, cell-based assays to study this phenomenon in cells.
- Troubleshot and validated protocols and assays to determine the pH environment in which amino alcohols generated maximum superoxide, with the scope of attaching them to targeting monoclonal antibodies.
- Wrote abstracts and designed posters to present at international conferences.
Education
Ph.D. - Nutritional Sciences
Texas Tech University
Lubbock, Texas, USA12.2015
Post Graduate Diploma - Dietetics
SNDT Women's University
Mumbai, India01.2010
Master of Science - Biochemistry
University of Mumbai
Mumbai, India05.2008
Bachelor of Science - Life Sciences & Biochemistry
University of Mumbai
Mumbai, India05.2006
Skills
- In vitro/In vivo study design
- Mammalian cell culture
- RT-PCR
- Transfection
- microRNA, RNA, DNA extraction
- Cell-based assays: MTT, ROS detection
- Light microscopy, live cell imaging
- SDS-PAGE, Western blotting
- ELISA
- Chemiluminescence
- RP-HPLC
- In vivo: Breast and Prostate Cancer models
- Injections - IP/SQ/Intracardiac/Intracranial
- In vivo Imaging
- Microsoft Office, ImageJ, Electronic Notebook
- GraphPad Prism
- IBM SPSS
- Reactome- cDNA microarray analysis
- Grant writing, scientific writing
- Project Management
Certification
- Foundations of Project Management – Google- August 2024
- Introduction to Generative AI- Google- April 2024
Publications
https://scholar.google.com/citations?user=hc7-kEAAAAAJ&hl=en
Timeline
Post-Doctoral Fellow
Thomas Jefferson University
05.2019 - 10.2023
Postdoctoral Research Associate/Laboratory Manager
Texas Tech University
02.2016 - 08.2017
Lead Teaching Assistant
Texas Tech University
01.2011 - 12.2015
Ph.D. Candidate
Texas Tech University
01.2011 - 12.2015
Ph.D. - Nutritional Sciences
Texas Tech University
Post Graduate Diploma - Dietetics
SNDT Women's University
Master of Science - Biochemistry
University of Mumbai
Bachelor of Science - Life Sciences & Biochemistry
University of Mumbai