Michelle Austin

Collaborative leader with dedication to partnering with coworkers to promote engaged, empowering work culture. Documented strengths in building and maintaining relationships with diverse range of stakeholders in dynamic, fast-paced settings. Hardworking and passionate job seeker with strong organizational skills eager to secure entry-level Job Title position. Ready to help team achieve company goals. Detail-oriented team player with strong organizational skills. Ability to handle multiple projects simultaneously with a high degree of accuracy. To seek and maintain full-time position that offers professional challenges utilizing interpersonal skills, excellent time management and problem-solving skills.

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• Clinical Trial
• Effects of the anti-migraine drug sumatriptan on muscle energy metabolism: relationship to side- effects
• M D Boska et al
• Cephalalgia
• 2000 Feb
• Show details
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• Abstract
• Sumatriptan succinate (Imitrex) is a 5-HT (5- hydroxytryptamine) agonist used for relief of migraine symptoms
• Some individuals experience short-lived side-effects, including heaviness of the limbs, chest heaviness and muscle aches and pains
• The effects of this drug on skeletal muscle energy metabolism were studied during short submaximal isometric exercises
• We studied ATP flux from anaerobic glycolysis (An Gly), the creatine kinase reaction (CK) and oxidative phosphorylation (Ox Phos) using 31P nuclear magnetic resonance spectroscopy (31P MRS) kinetic data collected during exercise
• It was found that side-effects induced acutely by injection of 6 mg sumatriptan succinate s.c
• Were associated with reduced oxygen storage in peripheral skeletal muscle 5-20 min after injection as demonstrated by a transient reduction in mitochondrial function at end-exercise
• These results suggest that mild vasoconstriction in peripheral skeletal muscle is associated with the action of sumatriptan and is likely to be the source of the side-effects experienced by some users
• Migraine with aura patients were more susceptible to this effect than migraine without aura patients
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• Dahlöf C
• Cephalalgia
• 1999
• PMID: 10526675

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