Diligent scientist with a solid foundation in research methodologies and data analysis. Effectively contributed to multiple research projects, showcasing keen eye for detail and problem-solving abilities. Demonstrated strong collaboration and critical thinking skills in both independent and team-driven environments.
Overview
11
11
years of professional experience
Work History
Postdoctoral Fellow
Yale University
06.2024 - Current
Designed robust experiments that produced reliable data.
Maintained record of research findings with analysis and evaluation of results.
Built and maintained professional relationships with students and faculty members.
Graduate Research Assistant
The University of Texas Health Science Center
09.2017 - 03.2024
Generated lentiviruses and retroviruses for the purpose of engineering cell lines.
Designed and engineered stable cell lines with gene knock-outs and gene overexpression.
Designed and engineered the endogenous gene knock-in cell lines using CRISPR and single-stranded Donor Oligonucleotides
Performed routine lab experiments such as immunofluorescent microscopy, western blots, PCR, qRT-PCR, and RNA-sequencing library preparations.
Participated in regular meetings with project supervisors, providing progress updates and discussing potential challenges or areas for improvement.
Assisted in manuscript preparation, contributing to the publication of influential articles in peer-reviewed journals.
Worked as member of integrated project team in highly collaborative work environment.
Graduate Research Assistant
Tulane University
09.2015 - 05.2017
Worked with mice and mouse embryos for the purpose of immunohistochemistry.
Used CRISPR to engineering gene knock-out cell lines.
Taught Microbiology laboratory to undergraduate students including preparation of weekly short lectures, lab set-up and quizzes.
Assisted in teaching Cell Biology course to undergraduate students.
Laboratory Technician
Health Diagnostics and Research Institute
03.2014 - 03.2015
Maintained a high level of accuracy in test results by following strict quality control procedures.
Cleaned and sterilized tools and equipment to maximize purity of specimens.
Performed testing and quality control using approved laboratory procedures and instrumentation.
Collected and processed patients' samples for downstream analysis.
Education
Ph.D. - Integrated Biomedical Sciences
The University of Texas Health Science Center
San Antonio, TX
05-2024
Master of Science - Biotechnology
The University of Texas At San Antonio
San Antonio, TX
05-2013
Bachelor of Arts - Biochemistry
Drew University
Madison, NJ
05-2011
Skills
Engineering of transient gene overexpression and knock-down cell lines
Engineering of stable gene knock-out and knock-in as well as overexpressing cell lines
Routine laboratory techniques (eg ELIZA, PCR, qRT-PCR, Western Blot, IF)
Exceptional written and oral communication
Collaborative research
Experimental design
Scientific writing
Teaching experience
Accomplishments
Publications:
Shamby, R., Li H., Kabeche, L. 2024. CENP-A: Cracking the code – Ins and Outs of CENP-A Post-Translational Modifications. Journal of Cell Biology. Submitted.
Muralimanoharan S, Shamby R, Stansbury N, Schenken R, de la Pena Avalos B, Javanmardi S, Dray E, Sung P, Boyer TG. Aberrant R-loop-induced replication stress in MED12-mutant uterine fibroids. Sci Rep, 2022; 12: 6169
Ye W, Song Y, Huang Z, Osterwalder M, Ljubojevic A, Xu J, Bobick B, Abassah-Oppong S, Ruan N, Shamby R, Yu D, Zhang L, Cai CL, Visel A, Zhang Y, Cobb J, Chen Y. A unique stylopod patterning mechanism by Shox2-controlled osteogenesis. Development. 2016 Jul 15;143(14):2548-60. doi: 10.1242/dev.138750
Timeline
Postdoctoral Fellow
Yale University
06.2024 - Current
Graduate Research Assistant
The University of Texas Health Science Center
09.2017 - 03.2024
Graduate Research Assistant
Tulane University
09.2015 - 05.2017
Laboratory Technician
Health Diagnostics and Research Institute
03.2014 - 03.2015
Ph.D. - Integrated Biomedical Sciences
The University of Texas Health Science Center
Master of Science - Biotechnology
The University of Texas At San Antonio
Bachelor of Arts - Biochemistry
Drew University
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