URVAL PATEL
Ankeny,IA
Summary
Graduate Research Assistant with expertise in biochemistry and biophysics, specializing in LLPS, protein purification, and molecular simulations. Led projects on ATF4 and ATF5, developed novel protocols, and integrated NMR, microscopy, and computational approaches. Contributed to two peer-reviewed publications. Demonstrated leadership as BBMB Department Senator, aspiring to leverage scientific expertise, collaboration, and teamwork to drive innovation and lead in biotech and pharma.
Overview
5
5
years of professional experience
Work History
Senator for Graduate and Professional Student Senate
Iowa State University
Ames, USA
08.2024 - Current
Biochemistry and Biophysics Graduate Research Assistant
Iowa State University
Ames, USA
01.2021 - Current
- Led advanced research in biochemistry and biophysics, exploring liquid–liquid phase separation and its role in cellular processes.
- Designed and optimized 4 novel experimental protocols and developed innovative methods for recombinant protein isolation from inclusion bodies.
- Managed multiple projects, including experimental and computational studies on ATF4 and ATF5, and performed 15 all-atom molecular dynamics simulations to analyze protein conformations, RMSD, contact maps, and PCA.
- Executed NMR spectroscopy and microscopy-based experiments to validate structural and functional hypotheses, integrating computational insights with experimental data.
- Successfully cloned and expressed 20–30 constructs for protein purification; conducted in vitro and in vivo functional assays to support research objectives.
- Delivered accurate data interpretation and analysis, contributed to peer-reviewed publications, and mentored 3–4 graduate students in FPLC usage and core lab techniques while teaching undergraduate coursework.
Associate Lab Technologist
PerkinElmer
Valencia, USA
11.2020 - 07.2021
- Operated and troubleshooted the automated Che-Magic 360D for SARS-CoV-2 RNA extraction.
- Prepared samples using aseptic techniques and maintained sterile environments.
- Adhered to SOPs in a CLIA-certified laboratory, ensuring compliance and efficacy of clinical testing.
- Documented and reviewed QC batch records in LIMC utilizing good documentation practices.
Education
Ph. D - Biochemistry and Biophysics
Iowa State University
Ames, IA10-2026
Bachelor of Science - Biotechnology
California State Polytechnic University
Pomona, CA01.2020
Skills
Experimental Techniques: Protocol development & optimization; Molecular cloning (Gibson Assembly, restriction ligation); Site-directed mutagenesis; Recombinant protein purification & characterization; Assay development (Luciferase, Turbidity); DNA-binding assays (FP, NMR, EMSA); Microscopy
Equipment: NMR, AKTA Pure FPLC, CD spectrometer, Confocal microscope, UV-Vis spectrometer, Multimode plate readers
Laboratory Skills: E coli & HEK293 cell culture; PCR; Electrophoresis; SDS-PAGE; Western blot; Chromatography (Affinity, Ion Exchange, SEC); Lab inventory management
Computational: All-atom simulations (GROMACS); Coarse-grain modeling; Data analysis (Python, Unix)
Software: GROMACS, PyMOL, Sparta, Larmorca, SnapGene, Unicorn, Leica, Zeiss, Gen5, Microsoft Suite
Transferable Skills: Scientific writing & reporting; Team collaboration; Problem-solving; Time management
Leadership Experience
Senator for Graduate and Professional Student Senate, Iowa State University, Ames, IA, 08/2024, Present
Timeline
Senator for Graduate and Professional Student Senate
Iowa State University
08.2024 - Current
Biochemistry and Biophysics Graduate Research Assistant
Iowa State University
01.2021 - Current
Associate Lab Technologist
PerkinElmer
11.2020 - 07.2021
Ph. D - Biochemistry and Biophysics
Iowa State University
Bachelor of Science - Biotechnology
California State Polytechnic University