Ye Htut Oo
Fremont,CA
Summary
Dynamic Histotechnologist with extensive experience at Exact Sciences, skilled in immunohistochemistry and tissue processing. Proven track record in developing standard operating procedures and enhancing laboratory workflows. Adept at regulatory compliance and data documentation, while providing training and guidance to peers, ensuring high-quality results in histopathology.
Overview
14
14
years of professional experience
1
1
Certification
Work History
Histotechnologist 2
Exact Sciences
Redwood City, CA
10.2018 - Current
- Perform routine and non-routine activities involved in histology, to include sectioning and hematoxylin and eosin (H&E) staining under supervision.
- Independently monitor and process the histology queue for various tasks that need to be performed, with minimal supervision.
- Perform macro-dissection of samples.
- Process samples through the internal Immunohistochemistry (IHC) stain process, as well as quality assurance (QA) and quality control (QC) activities associated with IHC under supervision.
- Prepare reagents, solutions, and controls.
- Perform and document equipment maintenance and calibration.
- Assist in sample returns, as needed.
- Process specimens for research and development sponsored studies.
- Assist in the identification of opportunities for process improvements for Exact Sciences histopathology.
- Assist in workflow, protocol, and related SOP development.
- Assist in equipment specification, installation, and maintenance.
- Provide guidance and training to research and development (R&D) staff relating to histopathology.
- Provide summary reports on process metrics, as needed.
- Training new staff as appropriate for function.
- Perform competency assessment
Histotechnologist 1
Exact Sciences
Redwood City, CA
10.2018 - 09.2022
- Perform routine and non-routine activities involved in Histology including sectioning and H&E Staining.
- Perform Microdissection of Samples.
- Perform and document equipment maintenance and calibration.
Histotechnologist
Covance
Los Angeles, CA
05.2017 - 07.2018
- Performed routine histological procedures including grossing, processing, embedding, sectioning.
- Stain IHC and ISH using Dako Autostainer, Leica Bond lll, Bond Rx, Ventana BenchMark Ultra.
- Stain PDL-1 marker on clinical trial samples for Phase11 and lll studies using Dako IHC autostainer Link 48 and troubleshoot the related staining issues.
- Validate new antibodies and RNAscope on Leica Bond III and Ventana Bench Mark Ultra.
- Provided technical and administrative support to the department supervisor.
- Train new lab employees on lab techniques and procedures, documentation practices.
- Comply with safety regulations, SOPs, GLPs, and study protocols and assist with development and revision of SOPs.
Histotechnologist
The Nebraska Medical Center
Omaha, NE
11.2015 - 04.2017
- Responsible for detail work in cutting, staining, and mounting tissue sections on slides for various type of tissue, IHC/ISH and special staining systems while using a surgical Co-Path Plus tracking system.
- Prepare renal and skin specimens for frozen sectioning.
- Load and unload specimens for fixation and tissue processing according to tissue type.
Research Associate
Singhealth Tissue Repository
Singapore
11.2010 - 05.2015
- Company Overview: AMPL
- Harvesting the tumor tissue by dissecting the various specimens received from Surgical OR and facilitating the release the samples to research group within targeted time frame.
- Handling, processing and harvesting of various specimens such as Breast, Colon, Uterus, Edometrium, Stomach and Lung and assist in grossing, trimming with pathology residents.
- Fixing tissue using formalin.
- Embedding, sectioning, staining with H&E with auto stainer within time frame.
- Checking and studying routine H&E slides under microscope for quality control.
- In depth experience in antibody preparation and immunohistochemical staining using both manual and automatic stainer.
- Experience with optimizing new antibodies using microwave and pressure cooker microwave.
- Experience with performing fluorescent in situ hybridization (FISH), double immunofluorescence.
- Experience with establishing tissue microarray on paraffin block for all common tumors.
- Responsible for general housekeeping of laboratory to ensure clean and safe environment and maintaining laboratory equipment.
- Familiar with handling and storage of chemical, hazardous materials with appropriate safety training instructions.
- Maintain proper documentation in compliance with CAP guideline and regulation.
- AMPL
Education
Master of Public Health (MPH) -
Northern Illinois University
DeKalb, IL12-2022
Bachelor of Medicine and Surgery -
University of Medicine 1
Yangon05-2007
Skills
- Immunohistochemistry techniques
- Tissue processing and specimen preparation
- Standard operating procedure development
- Data documentation and compliance
- Process improvement strategies
- Regulatory adherence
- Laboratory information systems
Certification
- American Society for Clinical Pathology(ASCP)-International Histotechnologist (HTL)
- The Qualification in Immunohistochemistry (QIHC)
Languages
English
Professional
Burmese
Native/ Bilingual
Timeline
Histotechnologist 2
Exact Sciences
10.2018 - Current
Histotechnologist 1
Exact Sciences
10.2018 - 09.2022
Histotechnologist
Covance
05.2017 - 07.2018
Histotechnologist
The Nebraska Medical Center
11.2015 - 04.2017
Research Associate
Singhealth Tissue Repository
11.2010 - 05.2015
Master of Public Health (MPH) -
Northern Illinois University
Bachelor of Medicine and Surgery -
University of Medicine 1
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