Summary
Overview
Work History
Education
Skills
Accomplishments
Certification
Languages
Work Availability
Interests
Quote
Timeline
Publications
Honors And Awards
Selected Publications
Generic

Elisabet Caler, PhD

Silver Spring,MD

Summary

Accomplished PhD scientist and Senior Science Advisor with extensive expertise in biomedical research, molecular and celular biology, microbial pathogenesis, immunology, and bioinformatics. Demonstrated leadership in research portfolio management and large-scale project development, complemented by a strong publication record in top-tier journals such as Science and Nature. Proven ability to engage stakeholders effectively while advocating for diversity, inclusion, and teamwork in cross-cultural environments. Multilingual proficiency in English, Spanish, and French enhances communication across diverse teams.

Overview

23
23
years of professional experience
1
1
Certificate

Work History

Senior Scientific Advisor, Office of AIDS Research

National Institutes of Health, NIH
Bethesda, MD
10.2019 - Current

Responsibilities and Accomplishments.

  • Strategic Leadership: Led the development of a five-year research strategic plan, providing expert guidance in shaping the future direction of HIV/AIDS biomedical research investments and aligning them with organizational goals.
  • Program Evaluation and Optimization: Directed comprehensive evaluations of scientific programs, delivering strategic insights that enhanced the quality, impact, and alignment of key biomedical research initiatives.initiatives within the NIH HIV/AIDS portfolio.
  • Innovation and Capacity Building: Spearheaded high-impact initiatives in emerging technologies, workforce development, and community engagement, fostering innovation, and driving sustainable growth within the research ecosystem.
  • Cross-Institutional Collaboration: Orchestrated research activities across multiple institutions, optimizing resources, and enhancing collaboration to minimize duplication and maximize the effectiveness of research investments.
  • Infrastructure Development: Designed and executed key initiatives to fortify research infrastructure, ensuring long-term scientific advancement, and continuous operational improvements.
  • Strategic Financial Oversight: Provided expert strategic advice on the 3.2B Office of AIDS Research budget allocation across NIH 23 Institutes and Offices, ensuring the optimal deployment of research funding to maximize overall impact, and support high-priority initiatives.
  • Stakeholder Engagement & Policy Influence: Acted as a key liaison to stakeholders and advisory committees within NIH and across other Agencies and Organizations, influencing high-level strategic decisions, and contributing to the development of policies that guide research priorities.

Program Director

National Heart Lung and Blood Institute
Bethesda, MD
05.2013 - 10.2019
  • Directed the Lung Response to Pulmonary Infections, Microbiome, HIV/AIDS, and Tuberculosis Program, managing a diverse portfolio of over 200 active research and training grants.
  • Authored and collaborated on 14 Funding Opportunity Announcements (FOAs) to drive innovation and investment in emerging research areas.
  • Conducted portfolio evaluations and risk analyses, identifying key scientific gaps, assessing clinical research grants, and ensuring strategic funding alignment.
  • Provided expert consultation to prospective grantees and trainees, guiding application development and enhancing funding success rates.
  • Reviewed grant proposals and supplements for scientific merit, developed pay-plan strategies, and presented program plans to NHLBI Council members.
  • Served as NHLBI Liaison for the Trans-NIH Microbiome and Tuberculosis Working Groups, Centers for AIDS Research (CFAR), and NHLBI AIDS Team (Lung Lead) to foster interagency collaboration.
  • Led and managed conference sessions for ASM, ATS, and Keystone, shaping scientific discussions and advancing research priorities.
  • Conducted site visits to evaluate project compliance and progress, ensuring alignment with program goals and funding objectives.

Assistant Professor

J. Craig Venter Institute (JCVI)
Rockville, MD
01.2009 - 05.2013
  • Led independent research in genomics, metagenomics, transcriptomics, and infectious disease, contributing to high-impact publications and advancing scientific knowledge.
  • Secured competitive funding through compelling grant proposals, driving innovative research initiatives.
  • Directed multidisciplinary teams of 10+ bioinformatics analysts, engineers, and support staff to execute large-scale genomics projects.
  • Investigated mobile genetic elements to uncover their role in genome evolution, enhancing understanding of genetic mobility and adaptation.
  • Chaired metadata working groups, establishing standardized procedures for eukaryotic genome annotation to improve data accuracy and interoperability.
  • Mentored post-graduate researchers at top-tier institutions including Yale, George Washington, and UMD, fostering the next generation of scientists.
  • Invited lecturer for genomics workshops and courses, sharing expertise and training researchers in cutting-edge methodologies.

Bioinformatics Scientist/Bioinformatics Manager

The Institute for Genomic Research (TIGR)
Rockville, MD
01.2007 - 03.2010
  • Eukaryotic Bioinformatics Team Lead
  • Project leader for NIAID funded project through the TIGR Microbial Sequencing Center
  • Implementation of innovative eukaryotic genome annotation workflows and pipelines
  • Developed and organized a graduate-level Microbial Genomics workshop University of Helsinki, Finland.

Senior Bioinformatics Analyst, Supervisor

The Institute for Genomic Research (TIGR)
Rockville, MD
04.2006 - 01.2007
  • Led genome sequencing, annotation, and analysis for multiple large-scale projects, ensuring high-quality deliverables.
  • Supervised and mentored a team of three Bioinformatics Analysts, managing task assignments, project progress, and performance evaluations.
  • Developed and conducted hands-on genome annotation workshops for diverse audiences, including students, postdocs, and investigators.

Bioinformatics Analyst

The Institute for Genomic Research (TIGR)
Rockville, MD
02.2002 - 04.2006

Conducted genome annotation and large-scale genomic analysis of human pathogens, including Trypanosoma, Leishmania spp., Plasmodium spp., Entamoeba spp., and Cryptococcus spp. Performed bioinformatics analyses, managed genome submissions, and ensured data accuracy and integrity. Additionally, prepared scientific presentations, contributed to publications, and collaborated with researchers to advance pathogen genomics and informatics initiatives. This work resulted in publications in high-impact journals, contributing to significant advancements in the understanding of these pathogens and their genomic landscapes.

Education

Fogarty Postdoctoral Fellow: Immunology, Microbial Pathogenesis -

National Institutes of Health, NIAID, Laboratory of Parasitic Diseases

Postdoctoral Research Associate: Microbial Pathogenesis and Cell Biology -

Boyer Center for Molecular Medicine

Ph.D. in Biomedical Sciences: Microbial Pathogenesis and Cell Biology -

Yale University School of Public Health

M.Phil.: Microbial Pathogenesis and Cell Biology -

Yale University School of Public Health

Visiting Scientist: Post M.Sc. Molecular Virology -

Plum Island Animal Disease Center (USDA)

M.Sc. in Biology: Molecular Biology and Biotechnology -

University of Buenos Aires School of Exact and Natural Sciences

Baccalaureate in Commercial Sciences; Minor: Biological Sciences -

Escuela Superior de Comercio Carlos Pellegrini, University of Buenos Aires

Skills

  • Leadership & Decision-Making – Provide clear direction, align decisions with strategic goals, and drive team success
  • Strategic Planning – Develop research strategies, optimize resources, and align initiatives for innovation and impact
  • Communication – Strong verbal and written skills to convey expectations, provide feedback, and address concerns effectively
  • Team Building & Collaboration – Foster trust, inclusivity, and teamwork to enhance productivity and innovation
  • Performance Management – Set goals, monitor progress, provide feedback, and implement performance improvement plans
  • Coaching & Mentorship – Guide professional growth by offering support, feedback, and development opportunities

Accomplishments

  • Designed and led high-impact research programs, fostering innovation in biomedical research, emerging technologies, and early-career investigator support.
  • Developed national and global initiatives to advance diagnostics, data-driven decision-making, and health equity, including workforce development programs and community engagement strategies.
  • Led the creation of data-driven platforms to promote transparency, resource-sharing, and workforce expansion in research.
  • Strategically identified and addressed critical scientific gaps by developing targeted funding initiatives, advancing research on infectious diseases, lung health, aging, and comorbidities.
  • Secured and managed competitive funding mechanisms, writing and presenting program proposals that shaped investment priorities in complex biomedical research fields.
  • Drove multi-stakeholder collaboration, working across institutions, industry partners, and government agencies to align research priorities and funding strategies.

Certification

Leadership & Professional Development Scientific & Regulatory Training

  • I LEAD Program – Advanced leadership training focused on strategic decision-making and organizational effectiveness.
  • NIH-NHLBI Leadership Programs – Completed multiple leadership and management programs, including the Leadership Lab, Emerging Leader Program, and Grey Matters: Critical Thinking & Decision-Making Skills.
  • Executive & Management Training – Courses in supervision, mentoring, and conflict resolution, enhancing team leadership and stakeholder engagement skills.
  • Advanced Immunology & Clinical Science – Completed specialized training in Basic Immunology, Human Microbiome, and FDA Regulatory Science.
  • Research Administration & Compliance – Certified Contracting Officer Representative (FAC-COR) with additional training in Appropriations Law, Federal Acquisition, and Clinical Investigator Regulations.
  • Ethics & Human Research Protections – Extensive training in IRB processes, human subject protections, and extramural research administration.

Languages

English
Native/ Bilingual
Spanish
Native/ Bilingual
French
Limited

Work Availability

monday
tuesday
wednesday
thursday
friday
saturday
sunday
morning
afternoon
evening
swipe to browse

Interests

Illustration, writing, water sports, community engagement, kindness Helping others

Quote

"You just can't beat the person who never gives up"
Babe Ruth

Timeline

Senior Scientific Advisor, Office of AIDS Research

National Institutes of Health, NIH
10.2019 - Current

Program Director

National Heart Lung and Blood Institute
05.2013 - 10.2019

Assistant Professor

J. Craig Venter Institute (JCVI)
01.2009 - 05.2013

Bioinformatics Scientist/Bioinformatics Manager

The Institute for Genomic Research (TIGR)
01.2007 - 03.2010

Senior Bioinformatics Analyst, Supervisor

The Institute for Genomic Research (TIGR)
04.2006 - 01.2007

Bioinformatics Analyst

The Institute for Genomic Research (TIGR)
02.2002 - 04.2006

Fogarty Postdoctoral Fellow: Immunology, Microbial Pathogenesis -

National Institutes of Health, NIAID, Laboratory of Parasitic Diseases

Postdoctoral Research Associate: Microbial Pathogenesis and Cell Biology -

Boyer Center for Molecular Medicine

Ph.D. in Biomedical Sciences: Microbial Pathogenesis and Cell Biology -

Yale University School of Public Health

M.Phil.: Microbial Pathogenesis and Cell Biology -

Yale University School of Public Health

Visiting Scientist: Post M.Sc. Molecular Virology -

Plum Island Animal Disease Center (USDA)

M.Sc. in Biology: Molecular Biology and Biotechnology -

University of Buenos Aires School of Exact and Natural Sciences

Baccalaureate in Commercial Sciences; Minor: Biological Sciences -

Escuela Superior de Comercio Carlos Pellegrini, University of Buenos Aires

Publications

Peer-reviewed scientific publications

https://www.ncbi.nlm.nih.gov/myncbi/lis.caler.1/bibliography/public/

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Other Invited reviews and book chapters

1. Entamoeba histolytica: Genome Status and Web Resources. Elisabet Caler and Hernan Lorenzi. Anaerobic Parasitic Protozoa: Genomics and Molecular Biology. Publisher: Caister Academic Press. March 2010.

2. Fernández Robledo JA, Caler E, Matsuzaki M, Keeling PJ, Roos DS, Vasta GR. The search for the missing link: A relic plastid in Perkinsus? Int J Parasitol. 2011, Aug 22. PMID: 21889509.

3. Kiley JP, Caler EV. The lung microbiome. A new frontier in pulmonary medicine. Ann Am Thorac Soc. 2014 Jan;11 Suppl 1:S66-70. doi: 10.1513/AnnalsATS.201308-285MG. PMID:2443741

4. Zou S, Caler L, Colombini-Hatch S, Glynn S, Srinivas P. Research on the human virome: where are we and what is next. Microbiome. 2016 Jun 24;4(1):32. doi: 10.1186/s40168-016-0177-y. PMID: 27341799

Honors And Awards

Honors & Awards

  • Fellows Program, Yale University – Fellowship Award (1994–1996)
  • NIH Fogarty International Center – Postdoctoral Fellowship (2000–2002)
  • NHLBI Director’s Award for Partnership & Collaboration (2013, 2017)
  • NHLBI Group Awards – Recognized for excellence in biomedical research and collaboration (2015, 2016, 2017, 2018)
  • NIH OD Honor Award – OAR Working Group for HIV Early Career Investigators (2021)
  • NIH OD Honors Award – HIV & Aging Working Group (2023) – For developing an action plan to support interdisciplinary research and training for aging populations with HIV
  • NIH OD Honors Award – OAR Data Hub Team (2023) – For the successful launch of the NIH OAR Data Hub, showcasing the NIH HIV Research Portfolio
  • NIH OD Honors Award – Advanced Technologies for HIV Diagnostics Team (2023) – For implementing an action plan to advance HIV diagnostic technologies and care
  • Office of AIDS Research Special Act Award (2023)
  • NIH Office of the Director Award for Excellence (2024) – For championing a data-driven, equity-informed approach to HIV research, particularly focused on women

Selected Publications

Peer Reviewed Publications

https://www.ncbi.nlm.nih.gov/myncbi/lis.caler.1/bibliography/public

Reports, reviews, executive summaries and book chapters
1. Entamoeba histolytica: Genome Status and Web Resources. Elisabet Caler and Hernan Lorenzi. Anaerobic Parasitic Protozoa: Genomics and Molecular Biology. Publisher: Caister Academic Press. March 2010.
2. Fernández Robledo JA, Caler E, Matsuzaki M, Keeling PJ, Roos DS, Vasta GR. The search for the missing link: A relic plastid in Perkinsus? Int J Parasitol. 2011, Aug 22. PMID: 21889509.

Elisabet V. Caler, Ph.D. Last updated September 2024

3. Kiley JP, Caler EV. The lung microbiome. A new frontier in pulmonary medicine. Ann Am Thorac Soc. 2014 Jan;11 Suppl 1:S66-70. doi: 10.1513/AnnalsATS.201308-285MG. PMID:2443741
4. Zou S, Caler L, Colombini-Hatch S, Glynn S, Srinivas P. Research on the human virome: where are we and what is next. Microbiome. 2016 Jun 24;4(1):32. doi: 10.1186/s40168-016-0177- y. PMID: 27341799

5. NIH OAR Second HIV Stakeholder Outreach and Engagement Report: September 2020– July 2021
6. The NIH OAR HIV Partner Outreach and Engagement Report: August 2021 to December 2022

7. Community Voices: Forging the Path Forward for HIV Self-Testing and Personalized Viral Load Monitoring - Executive Summary
8. 2024 Workshop for Early Career Investigators in HIV  - Executive Summary

Elisabet Caler, PhD