Jeehyun Karen You
Cleveland,OH
Summary
Highly-motivated MD-PhD candidate pursuing flexible part-time employment with weekend and evening shift options. Strong work ethic, adaptability, and exceptional interpersonal skills. Adept at working effectively unsupervised and quickly mastering new skills.
Overview
14
14
years of professional experience
1
1
Certification
Work History
MD-PhD Candidate
Case Western Reserve University, School Of Medicine
Cleveland, OH
07.2021 - Current
- NIH-funded Medical Scientist Training Program (MSTP) trainee currently conducting highly translational biomedical research as a Biochemistry PhD candidate following successful completion of pre-clinical medical education and STEP 1 board examination.
- Coursework includes: structural and computational biology; drug design; proteins and enzymes
- Research focuses on the role of genomic, transcriptomic, and post-translational regulation of gasdermin B-mediated intestinal epithelial cell function in inflammatory bowel disease (IBD).
Research Scientist
Stony Brook University
Stony Brook, NY
08.2019 - 06.2021
- Elucidated the role of sphingolipids in cryptococcosis, an invasive fungal infection caused by Cryptococcus neoformans.
- Determined how Fingolimod, an approved therapeutic for remitting multiple sclerosis, reactivates latent cryptococcal infections by leveraging a unique mouse model.
- Utilized various biochemical techniques to characterize how cholesterol-dependent lipid rafts mediate phagocytosis of the C. neoformans by macrophages.
- Developed a drug screening assay to identify small organic molecules that inhibit fungal ceramide synthase, a novel antifungal drug target.
- Collaborated with other researchers from different departments to develop more effective strategies for conducting experiments.
- Assisted in writing grant proposals for additional funding opportunities for ongoing projects.
- Reviewed scientific papers submitted for peer review for the Journal of Biological Chemistry.
Research Support Specialist
Stony Brook University
Stony Brook, NY
08.2016 - 08.2018
- Managed laboratory operations both at Stony Brook University and Northport Veterans' Affairs facilities.
- Laboratory responsibilities included: radiation safety permit approvals and renewals; animal study protocol approvals, renewals, and amendments; biosafety protocol approvals, renewals, and amendments.
- Performed budget management in concert with the offices of grant management and procurement.
- Onboarded laboratory personnel and trained graduate students on microbiology, molecular biology, lipid biochemistry, microscopy, cell culture, in vivo mouse study, flow cytometry, and histology protocols.
Clinical Research Assistant
Stony Brook University Medical Center
Stony Brook, NY
03.2011 - 09.2017
- Collaborated with sponsors and investigators to carry out efficient and fully compliant research trials.
- Conducted literature reviews to develop research projects and identify relevant resources.
- Prepared study protocols and informed consent documents for clinical trials.
- Developed tracking systems for regulatory submissions including IRB applications and amendments, IND Safety Reports.
- Performed data entry, organized and maintained participant records, monitored patient safety and prepared reports.
- Reviewed medical information from source documents to verify accuracy of CRF entries prior to database lock.
- Coordinated with clinical sites to ensure timely collection of data points throughout the course of a study.
- Monitored compliance with Good Clinical Practices, International Council on Harmonization guidelines, and applicable regulations.
- Participated in site visits with study sponsors to ensure adherence to protocol requirements, review source documentation, and provide guidance as needed.
- Maintained accurate records of all activities related to the conduct of clinical studies including correspondence files, contracts.
- Analyzed data collected from various sources such as laboratory results or patient questionnaires for quality assurance purposes.
- Organized, analyzed and modeled study data.
- Prepared study summary reports for investigators and sponsors using statistical software, such as SAS, SPSS, and GraphPad Prism.
- Interacted with vendors to obtain supplies necessary for conducting clinical trials such as lab kits or medication samples.
- Assessed records of each patient, reviewed databases and checked referrals to locate potential research study participants.
- Educated clinical study participant and addressed concerns.
- Conducted patient interviews to gather health history, vital signs and information about current medical issues.
Education
Master of Science - Physiology And Biophysics
SUNY Stony Brook
Stony Brook, NY05-2019
Bachelor of Science - Biochemistry
SUNY Stony Brook
Stony Brook, NY08-2018
M.D., Ph.D. - Ph.D. in Biochemistry
Case Western Reserve University
Cleveland, OHSkills
- Project Management
- Analytical and Critical Thinking
- Problem-Solving
- Study Design
- Data Analysis
- Experiment protocol development
- Advanced Research Techniques
- Grant Writing
- Manuscript writing and publication
- Clinical Support
Languages
English
Native/ Bilingual
Korean
Native/ Bilingual
Spanish
Professional
Accomplishments
- CWRU Graduate Student Travel Award- 2024
- CWRU MSTP Travel Award- 2024
- Research Recognition, In Faculty Opinions, 14 Dec 2020; 10.3410/f.738066999.793580714
- 4 first/co-first author research publications in: British Journal of Surgery (2018), Surgical Technology International (2018), Journal of Clinical Investigation (2020), and Journal of Biological Chemistry (2021).
- Co-authorship on a patent entitled "Methods of inhibiting fungal ceramide synthase for treatment of Cryptococcus neoformans infection." (2020)
Affiliations
- Ballet
- Swimming
- Wind ensemble
Certification
- Previously an American Red Cross certified lifeguard, water safety instructor, and lifeguarding instructor for 10+ years.
Timeline
MD-PhD Candidate
Case Western Reserve University, School Of Medicine
07.2021 - Current
Research Scientist
Stony Brook University
08.2019 - 06.2021
Research Support Specialist
Stony Brook University
08.2016 - 08.2018
Clinical Research Assistant
Stony Brook University Medical Center
03.2011 - 09.2017
Master of Science - Physiology And Biophysics
SUNY Stony Brook
Bachelor of Science - Biochemistry
SUNY Stony Brook
M.D., Ph.D. - Ph.D. in Biochemistry
Case Western Reserve University
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