Oluwatomisin Opaleye
Santa Clara,US
Summary
Senior bioengineering student on the biomolecular track. Passionate about working at the intersection of therapeutics and computational modeling to design innovative biopharma solutions.
Overview
3
3
years of professional experience
Work History
Senior Design Project
Santa Clara University
Santa Clara, CA
09.2025 - Current
- Conducted a year-long NIIMBL-funded capstone project in a team in collaboration with industry partners, focused on advancing biomanufacturing process optimization.
- Designed a computational framework to improve decision-making in biopharmaceutical formulation and production design.
- Applied statistical and computational analysis to evaluate experimental data, and enhance system performance and reproducibility.
- Utilized code for modeling, data visualization, and performance assessment.
- Integrated Good Manufacturing Practice (GMP) and Quality by Design (QbD) principles are used to ensure scalability and industry relevance.
Bio-device Engineering
Santa Clara University
Santa Clara, CA
09.2025 - 12.2025
- Designed and prototyped a non-invasive electrochemical biosensor for lactic acid detection to simulate real-world biodevice development.
- Conducted biomaterial selection, circuit design, and calibration for sensor accuracy and reproducibility.
- Managed a $100 project budget and generated technical documentation, including a blueprint and performance analysis report.
- Integrated biological, chemical, and electrical components to create a functional prototype suitable for healthcare and biochemical applications.
Undergraduate Student Research Assistant
Santa Clara University
Santa Clara, CA
01.2025 - 06.2025
- Conducted an AI-assisted redesign of the mitochondrial TIM/TOM translocase mechanism, enabling an improved understanding of protein import pathways.
- Developed a bioinformatics pipeline and custom biodatabase to model mitochondrial protein transport, and predict translocation efficiency.
- Built and trained a small language model (SLM) to identify key peptide motifs involved in the TIM/TOM mechanism, filtering irrelevant sequence data using AI-driven selection algorithms.
- Applied computational protein design to engineer and simulate CRISPR-Cas9 delivery into mitochondria, paving the way for targeted mitochondrial genome editing in oncology and longevity research.
- Performed literature reviews on protein synthesis, membrane transport, and CRISPR-Cas9 mechanisms, integrating findings into experimental and computational design frameworks.
Protein expression and purification
Santa Clara University
Santa Clara, CA
01.2025 - 03.2025
- Executed protein purification via His-tag affinity chromatography and analyzed samples using SDS-PAGE and Western blotting.
- Employed FPLC and liquid chromatography for effective protein separation and quantification.
- Conducted molecular modeling and docking simulations to explore protein–ligand interactions, guiding engineering strategies.
- Maintained comprehensive lab notebooks and prepared formal technical reports summarizing experimental designs and outcomes.
Bronco Assessment Student Ambassador
Santa Clara University
Santa Clara, CA
09.2022 - 06.2024
- Conducted literature reviews and background research on educational assessment methodologies to support departmental initiatives.
- Maintained organized records of assessment activities and data, ensuring compliance with institutional policies and procedures.
- Assisted in the collection and analysis of student performance data, utilizing statistical software to evaluate assessment results and identify trends.
- Contributed to the preparation of assessment reports and presentations, summarizing findings and recommendations for faculty and administration.
Education
Bachelor of Science - Bioengineering
Santa Clara University
Santa Clara, CA06.2026
Timeline
Senior Design Project
Santa Clara University
09.2025 - Current
Bio-device Engineering
Santa Clara University
09.2025 - 12.2025
Protein expression and purification
Santa Clara University
01.2025 - 03.2025
Undergraduate Student Research Assistant
Santa Clara University
01.2025 - 06.2025
Bronco Assessment Student Ambassador
Santa Clara University
09.2022 - 06.2024
Bachelor of Science - Bioengineering
Santa Clara University